Peripheral Artery Disease Clinical Trials

66 recruitingLast updated: June 18, 2026

There are 66 actively recruiting peripheral artery disease clinical trials across 19 countries. Studies span Not Applicable, Phase 3, Early Phase 1, Phase 2, Phase 1, Phase 4. Top locations include Chicago, Illinois, United States, Minneapolis, Minnesota, United States, Omaha, Nebraska, United States. Updated daily from ClinicalTrials.gov.


Peripheral Artery Disease Trials at a Glance

66 actively recruiting trials for peripheral artery disease are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 36 trials, with the heaviest enrollment activity in Chicago, Minneapolis, and Omaha. Lead sponsors running peripheral artery disease studies include Northwestern University, VA Office of Research and Development, and James Cook University.

Browse peripheral artery disease trials by phase

Treatments under study

About Peripheral Artery Disease Clinical Trials

Looking for clinical trials for Peripheral Artery Disease? There are currently 61 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral Artery Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral Artery Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 66 trials

Recruiting
Not Applicable

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy

DyslipidemiasPeripheral Vascular DiseasesPeripheral Artery Disease
Brigham and Women's Hospital400 enrolled1 locationNCT06300450
Recruiting

Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease

Peripheral Artery Disease
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer295 enrolled1 locationNCT07283289
Recruiting
Phase 3

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

Peripheral Artery Disease (PAD)
Regeneron Pharmaceuticals7,050 enrolled4 locationsNCT07318610
Recruiting
Not Applicable

Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia Stage

Peripheral Artery DiseaseMajor Adverse Cardiovascular EventsMajor Adverse Limb Events+2 more
Centre Hospitalier Universitaire, Amiens134 enrolled1 locationNCT06318767
Recruiting
Not Applicable

The THOR IDE Study

Peripheral Artery DiseasePADPeripheral Artery Stenosis+1 more
Philips Clinical & Medical Affairs Global155 enrolled29 locationsNCT05916950
Recruiting
Not Applicable

The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease

ClaudicationPeripheral Artery Disease
University of Oklahoma100 enrolled1 locationNCT05712395
Recruiting
Phase 3

The COCOA-PAD II Trial

Peripheral Artery Disease
Northwestern University190 enrolled3 locationsNCT04794530
Recruiting
Not Applicable

Detecting Peripheral Artery Disease With the Pulse

Peripheral Artery Disease (PAD)
University of Nebraska60 enrolled1 locationNCT07226193
Recruiting

The Value of Super-resolution Ultrasound Imaging for Peripheral Artery Disease

Peripheral Artery Disease
Peking University First Hospital300 enrolled1 locationNCT07374601
Recruiting
Not Applicable

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

Peripheral Artery DiseaseOverweight or Obesity
Northwestern University212 enrolled7 locationsNCT04228978
Recruiting

Serranator POINT FORCE Registry

Peripheral Artery Disease (PAD)Dysfunctional AV FistulaDysfunctional AV Graft
Cagent Vascular LLC500 enrolled19 locationsNCT06687590
Recruiting
Not Applicable

Telehealth Delivered Home-based Walking for Vets With Peripheral Artery Disease

Peripheral Artery Disease
VA Office of Research and Development225 enrolled3 locationsNCT06033924
Recruiting
Not Applicable

Stents Post-dilation With DCB or POBA in Femoropopliteal Arteries

Peripheral Artery Disease
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University180 enrolled3 locationsNCT03791970
Recruiting
Not Applicable

Red Light Treatment in Peripheral Artery Disease

Peripheral Artery DiseaseVasodilationClaudication, Intermittent
University of Alabama at Birmingham40 enrolled1 locationNCT03203239
Recruiting

REGistry of Long-term AnTithrombotic TherApy-1

Peripheral Artery DiseaseCoronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation2,000 enrolled1 locationNCT04347200
Recruiting
Not Applicable

Exercise Therapy for PAD Using Mobile Health

Peripheral Artery Disease
VA Office of Research and Development75 enrolled1 locationNCT04889105
Recruiting
Not Applicable

The Effects of Diet and Exercise Interventions in Peripheral Artery Disease

ClaudicationPeripheral Artery Disease
University of Oklahoma150 enrolled1 locationNCT03845036
Recruiting
Not Applicable

ENhancing Exercise With LIGHT to Improve Functioning in PAD

AgingWalking, DifficultyPeripheral Artery Disease+1 more
Northwestern University32 enrolled1 locationNCT06399900
Recruiting
Not Applicable

BEETroot Juice to Reverse Functional Impairment in PAD

Peripheral Artery Disease
Northwestern University210 enrolled4 locationsNCT05624125
Recruiting
Not Applicable

Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation

Diabetes MellitusPeripheral Artery DiseaseTranstibial amputation
VA Office of Research and Development54 enrolled2 locationsNCT03995238