Changes in Sensitivity, Taste and Smell in Stroke Patients
Changes in Sensitivity of Swallowing-relevant Structures, Taste and Smell in Stroke Patients
University of Giessen
200 participants
Oct 1, 2017
OBSERVATIONAL
Conditions
Summary
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients. Younger (\<60 years) and older (\>60 years) volunteers will serve as control.
Eligibility
Inclusion Criteria5
- Volunteers:
- informed consent
- Stroke patients:
- informed consent
- new supratentorial stroke (<72 hours old) confirmed by CT (computed tomography) or MRI (magnetic resonance imaging)
Exclusion Criteria4
- pre-existing stroke oder dysphagia
- extensive white matter lesions in CT- or MRI-scan
- allergies to odorous substances or flavoring
- contraindications for FEES (flexible endoscopic evaluation of swallowing), CT or MRI (stroke patients only)
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Interventions
Endoscopical swallowing study in stroke patients only
Determining sensitivity threshold using a pudendal electrode
Taste-/smell-test
Neuropsychological testing for neglect, agnosia
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03240965