Radiation Therapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer

This study is testing whether adding heat treatment (hyperthermia) to standard radiation and chemotherapy improves outcomes for women with advanced cervical cancer. **You may be eligible if...** - You have been confirmed (by tissue sample) to have cervical cancer - Your cancer is at an advanced stage (Stage IIB–IVA) or is at an earlier stage but surgery is not an option - You have not had the cancer spread to distant organs (except nearby lymph nodes) - You are 18 or older and in a reasonable general health state **You may NOT be eligible if...** - You have uncontrolled heart disease, heart failure, recent heart attack, or a pacemaker - You have metal implants larger than 2 cm in the pelvis - You have an active or treatment-resistant bladder infection - You have an immune deficiency condition - You are pregnant or breastfeeding - You are unwilling to use effective contraception during and after treatment Talk to your doctor to see if this trial is right for you.