Surveillance of Patients With Precancerous Lesions of the Stomach
Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach
University of Latvia
2,000 participants
Jun 19, 2017
OBSERVATIONAL
Conditions
Summary
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.
Eligibility
Inclusion Criteria1
- Patients undergoing upper endoscopy Motivation to participate in the study Signed consent
Exclusion Criteria1
- Known gastric cancer Unwillingness or inability to co-operate
Interventions
Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for histopathological examination, including H.pylori detection
Plasma/serum sampling will be used to obtain information for group stratification, e.g. H.pylori status determination, serum biomarkers
During upper endoscopy biopsies for gastric microbiota analysis will be obtained
Faecal samples will be obtained for faecal occult blood testing as well as microbiota analysis
Locations(1)
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NCT03250091