RecruitingNCT03265379

Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection

Sponsor

University Health Network, Toronto

Enrollment

104 participants

Start Date

Aug 22, 2017

Study Type

OBSERVATIONAL

Conditions

Breast Cancer

Summary

Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and is complicated by the fact that no prospective evidence exists evaluating the utility of FTCWR in prolonging survival or improving health related quality of life (HRQOL) and thus, there is a lack of evidence to guide treatment decisions. Gathering HRQOL, local-regional recurrence (LRR) and survival data in a prospective fashion is thus critical in this population. Therefore, we designed a prospective trial to evaluate the outcomes for FTCWR in terms of LRC and HRQOL, and short-term morbidity and mortality, with secondary focus on potential long-term overall survival benefit.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking outcomes and quality of life in breast cancer patients who need complex surgery to remove a tumor that has grown into the chest wall (ribs or surrounding tissue), to better understand recovery and long-term results. **You may be eligible if...** - You are over 18 with breast cancer confirmed to have grown into your chest wall (ribs, muscles, or nearby soft tissue) by imaging and biopsy - You are physically fit enough to undergo surgery - If your cancer is a local recurrence (came back), you have been disease-free for at least 1 year since your first treatment **You may NOT be eligible if...** - You have other medical conditions that make surgery too dangerous - The tumor cannot technically be fully removed - You are not a candidate for chemotherapy - Your general health and functional status are too poor (ECOG above 2) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERFACT-B and Brief Pain Inventory

Quality of Life Questionnaires

Locations(1)

University Health Network (Toronto General Hospital and Princess Margaret Cancer Centre)

Toronto, Ontario, Canada

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NCT03265379

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