RecruitingNCT03295279

WTC Chest CT Imaging Archive

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates


Sponsor

Icahn School of Medicine at Mount Sinai

Enrollment

2,122 participants

Start Date

Sep 1, 2012

Study Type

OBSERVATIONAL

Conditions

Summary

Dr. Rafael E de la Hoz and colleagues have performed standardized and computer-assisted readings of all chest CT scans received by WTC workers and volunteers at the Mount Sinai Medical Center between 2003 and 2016. The clinical team sought to assess all findings suggestive of airway, interstitial, and neoplastic disease in a systematic way, and correlate those findings with clinical, functional, and exposure indicators. The study team's research will also involve analyses of longitudinal imaging and functional trends, and characterization of the WTC related lower airway diseases and their risk factors, with a focus on obesity-related imaging markers. The study team also plans to characterize the transitions into chronic obstructive pulmonary disease (COPD) among these workers. The researchers also propose to test the use of added respiratory surveillance tools and explore functional markers of disease progression, explore alternate methods to investigate longitudinal functional trajectories, and novel spirometry calibration methods that might facilitate the implementation of spirometry in nonspecialized settings.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is creating an archive of chest CT scan images from people enrolled in the World Trade Center (WTC) Health Program — first responders, rescue workers, and survivors who were exposed to the toxic dust and fumes at Ground Zero — to study how WTC-related lung conditions change over time. **You may be eligible if...** - You are already enrolled in the screening/monitoring or treatment program at the WTC Health Program Clinical Center at Mount Sinai Medical Center in New York **You may NOT be eligible if...** - You are a fetus, newborn, pregnant woman, child, prisoner, or someone living in an institution — these groups are excluded from participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Icahn School of Medicine at Mount Sinai

New York, New York, United States

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NCT03295279


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