RecruitingNCT03299608

Rapid Analysis of Infections by Spectrometry of Exhaled Breath

Exhaled Breath Analysis for Rapid Diagnosis in Opportunistic Respiratory Infections in Hematological Patients

Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

246 participants

Start Date

Jun 21, 2019

Study Type

OBSERVATIONAL

Conditions

Hematologic Diseases Respiratory Tract Infections

Summary

To quantify the diagnostic, prognostic and therapeutic value of spectrometric analysis of exhaled breath from hematological patients with respiratory infection.

Eligibility

Min Age: 18 Years

Inclusion Criteria10

Age ≥ 18y at start of study
One of the following diagnoses:
De novo, refractory or relapsed AML/MDS receiving intensive chemotherapy
De novo, refractory or relapsed ALL/T-lymphoblastic lymphoma receiving intensive chemotherapy
Aplastic anemia requiring ATG therapy
Any patient admitted for either autologous hematopoietic stem cell transplantation. Transplantation may not have been performed at time of enrolment.
Any patient admitted with allogeneic hematopoietic stem cell transplantation within the last year, or planned during this admission.
Written informed consent obtained from the patient
Signs of active respiratory infection
If previously enrolled: incomplete clearance of all signs of respiratory infection (both clinically, microbiologically and radiologically).