RecruitingNCT03342144

Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting

Observational Study of the Use of Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting in Austria, Germany and Switzerland

Sponsor

AbbVie

Enrollment

500 participants

Start Date

Dec 4, 2017

Study Type

OBSERVATIONAL

Conditions

Chronic Lymphocytic Leukemia (CLL)

Summary

An observational study to assess the effectiveness, health economic-relevant costs and participant reported outcomes in participants with Chronic lymphocytic leukemia (CLL) receiving venetoclax as a monotherapy or in combination with rituximab, obinutuzumab, ibrutinib, or acalabrutinib as prescribed at the discretion of the physician and in accordance with local clinical practice and label.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a real-world observational study following patients with chronic lymphocytic leukemia (CLL) — a slow-growing blood cancer — who are starting treatment with venetoclax, to understand how well the drug works and what side effects occur in everyday clinical practice (outside of a controlled trial). **You may be eligible if...** - You have been diagnosed with CLL - You are starting venetoclax treatment as part of your standard care (in any line of treatment) - Your treatment follows the approved local guidelines for venetoclax **You may NOT be eligible if...** - You are not being treated with venetoclax - Your use of venetoclax does not follow the approved local guidelines Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Locations(70)

Universitaetsklinikum St. Poelten /ID# 221152

Sankt Pölten, Lower Austria, Austria

Medizinische Universitaet Graz /ID# 221155

Graz, Styria, Austria

Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 221153

Salzburg, Austria

Hanusch Krankenhaus /ID# 221151

Vienna, Austria

Stauferklinikum Schwaebisch Gmuend /ID# 201518

Mutlangen, Baden-Wurttemberg, Germany

Onkologische Praxis /ID# 201545

Stuttgart, Baden-Wurttemberg, Germany

Schwarzwald-Baar-Klinikum /ID# 208176

Villingen-Schwenningen, Baden-Wurttemberg, Germany

MVZ am Klinikum Aschaffenburg Onkologie /ID# 201548

Aschaffenburg, Bavaria, Germany

Studienzentrum Aschaffenburg /ID# 204125

Aschaffenburg, Bavaria, Germany

Gemeinschaftspraxis Dr. Heinrich und Prof. Bangerter /ID# 200950

Augsburg, Bavaria, Germany

Drs. Tanzer, Chirca, Stoeberl /ID# 202613

Bad Reichenhall, Bavaria, Germany

Internistische Schwerpunktpraxen, Erlangen /ID# 200949

Erlangen, Bavaria, Germany

Onkologie Hof /ID# 201531

Hof, Bavaria, Germany

Praxis Dr. Stauch /ID# 202611

Kronach, Bavaria, Germany

VK&K Studien GbR /ID# 202614

Landshut, Bavaria, Germany

Haemato-Onkologie /ID# 205236

Munich, Bavaria, Germany

Praxis Dr. Kreher /ID# 202604

Bad Liebenwerda, Brandenburg, Germany

Praxis Dres. Kiehl/Stein /ID# 210052

Frankfurt (Oder), Brandenburg, Germany

MVZ f. Blut- u.Krebserkrankungen /ID# 206704

Potsdam, Brandenburg, Germany

Ambulantes Tumorzentrum Bremerhaven /ID# 224353

Bremerhaven, Free Hanseatic City of Bremen, Germany

Centrum fuer Haematologie und Onkologie Bethanien /ID# 206701

Frankfurt am Main, Hesse, Germany

MVZ Dres. Cordes & Partner /ID# 202598

Frankfurt am Main, Hesse, Germany

Klinikum Frankfurt Hoechst /ID# 210048

Frankfurt am Main, Hesse, Germany

Praxis Dres. Tebbe/Mayer /ID# 206730

Kassel, Hesse, Germany

Onkologische Kooperation Harz /ID# 201550

Goslar, Lower Saxony, Germany

OAZ Hannover /ID# 201538

Hanover, Lower Saxony, Germany

Onkolologische Praxis Oldenburg /ID# 202607

Oldenburg, Lower Saxony, Germany

MVZ der Paracelsus-Klinik /ID# 201541

Osnabrück, Lower Saxony, Germany

Med. Studiengesellschaft Nord West GmbH /ID# 201535

Westerstede, Lower Saxony, Germany

Praxis Dres. Plewe/Losem /ID# 202606

Neuss, North Rhine-Westphalia, Germany

Hämatologie und Onkologie /ID# 205247

Kaiserslautern, Rhineland-Palatinate, Germany

Praxis Dr. Klaproth/Cura /ID# 216413

Neunkirchen, Saarland, Germany

Onkozentrum Dresden /ID# 202599

Dresden, Saxony, Germany

BAG Freiberg-Richter, Jacobasch, Illmer, Wolf /ID# 201532

Dresden, Saxony, Germany

Luebecker Oncology Practice /ID# 200952

Lübeck, Schleswig-Holstein, Germany

Friedrich-Ebert-Krankenhaus GmbH /ID# 206206

Neumünster, Schleswig-Holstein, Germany

Praxis Dres. Krober/Stosiek /ID# 206729

Regensburg, State of Berlin, Germany

Caritas-Krankenhaus gGmbH /ID# 243212

Bad Mergentheim, Germany

MVZ Klinikum Mittelbaden GmbH /ID# 206207

Baden-Baden, Germany

Praxis für Hämatologie und Onkologie /ID# 241763

Berlin, Germany

Onkologische Schwerpunktpraxis /ID# 200953

Berlin, Germany

Praxis am Volkspark /ID# 243195

Berlin, Germany

Onkologie am Segelfliegerdamm /ID# 202603

Berlin, Germany

Pioh Dres. Draube & Partner /ID# 239507

Cologne, Germany

Praxis Dres. Prange-Krex/Mohm /ID# 210049

Dresden, Germany

St. Georg Klinikum Eisenach gemeinnützige GmbH (GKE) /ID# 250200

Eisenach, Germany

Praxis fuer interdisziplinaere Onkolologie und Haematologie /ID# 206999

Freiburg im Breisgau, Germany

MVZ Onkologie GmbH /ID# 212376

Hagen, Germany

onkomedic GbR /ID# 218354

Halle, Germany

OncoResearch Lerchenfeld GmbH /ID# 205237

Hamburg, Germany

Onkologische Gemeinschaftspraxis /ID# 205239

Hamburg, Germany

Evangelisches Krankenhaus Hamm /ID# 206703

Hamm, Germany

Studienzentrum am Raschplatz /ID# 250180

Hanover, Germany

Studienbüro Kamal und Dorn GBR /ID# 234105

Hanover, Germany

Klinikum Idar-Oberstein GmbH /ID# 210046

Idar-Oberstein, Germany

Praxis Fuchs/Koehler /ID# 243215

Langenhessen, Germany

Bruederkrankenhaus St. Josef Paderborn /ID# 202600

Paderborn, Germany

Onkologische Praxis GbR /ID# 206705

Porta Westfalica, Germany

Praxis Dres. Decker/Lakner/Leithäuser /ID# 206208

Rostock, Germany

Diakonieklinikum Schwaebisch Hall /ID# 206205

Schwäbisch Hall, Germany

MVZ am Schlossgarten GmbH /ID# 210043

Schwetzingen, Germany

Kantonsspital Aarau AG /ID# 210034

Aarau, Canton of Aargau, Switzerland

Spital Thun /ID# 233714

Thun, Canton of Bern, Switzerland

Luzerner Kantonsspital /ID# 210029

Lucerne, Canton of Lucerne, Switzerland

Réseau Hospitalier Neuchâtelois /ID# 227865

Neuchâtel, Canton of Neuchâtel, Switzerland

Kantonsspital St. Gallen /ID# 223037

Sankt Gallen, Canton of St. Gallen, Switzerland

KSW Kantonsspital Winterthur /ID# 211068

Winterthur, Canton of Zurich, Switzerland

EOC Ospedale Regionale di Bellinzona e Valli /ID# 208782

Bellinzona, Canton Ticino, Switzerland

Kantonsspital Münsterlingen /ID# 210035

Münsterlingen, Thurgau, Switzerland

Inselspital, Universitaetsspital Bern /ID# 210031

Bern, Switzerland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03342144

Related Trials

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

NCT010873331 location

A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia

NCT072053152 locations

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

NCT057241211 location

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

NCT0513102262 locations

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

NCT0722150020 locations