RecruitingPhase 2NCT03398161

Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides

Ultra Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides


Sponsor

M.D. Anderson Cancer Center

Enrollment

50 participants

Start Date

Jan 6, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

This phase II trial studies how well ultra low dose radiation therapy works in treating patients with mycosis fungoides. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving ultra low doses of radiation may help control the disease and reduce side effects compared to treatment with higher doses.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether very low doses of targeted radiation therapy can effectively treat skin lesions caused by mycosis fungoides — a slow-growing type of lymphoma (blood cancer) that appears on the skin — with fewer side effects than higher-dose treatments. **You may be eligible if...** - You have been diagnosed with mycosis fungoides with active skin involvement, confirmed by tissue testing - You have at least one visible, measurable skin lesion - Your skin lesions are no more than 1 cm in height (thickness above the skin surface) in the area being treated - A single patient can have multiple eligible lesions treated at the same time **You may NOT be eligible if...** - Your skin lesions are taller than 1 cm above the skin surface - You do not have any measurable skin disease - You are unable to receive radiation therapy for other health reasons Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERQuality-of-Life Assessment

Ancillary studies

OTHERQuestionnaire Administration

Ancillary studies

RADIATIONRadiation Therapy

Undergo ultra low dose radiation therapy


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT03398161


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