Effects of Simvastatin on Uterine Leiomyoma Size

This trial is testing whether simvastatin — a common cholesterol-lowering medication — can reduce the size of uterine fibroids (non-cancerous growths in the uterus) and relieve symptoms like heavy menstrual bleeding in women who have symptomatic fibroids. **You may be eligible if...** - You are a woman between 18 and 55 years old - You have uterine fibroids diagnosed by ultrasound or MRI - You have at least one fibroid larger than 3 cm in diameter - Your fibroids are located inside the uterine wall or just beneath the lining (intramural or submucosal) - You have experienced heavy or prolonged menstrual bleeding in at least 3 of the last 6 cycles - Your BMI is under 45 kg per square metre - You have signed an informed consent form **You may NOT be eligible if...** - You are currently pregnant or planning to become pregnant during the study - You are post-menopausal or have had a prior fibroid treatment - You are currently taking medications that interact with simvastatin - Your fibroids are only located on the outside surface of the uterus Talk to your doctor to see if this trial is right for you.