Signal TrAnsduction Pathway Activity Analysis in OVarian cancER

This trial is analyzing tumor tissue from women with recurrent ovarian cancer to identify which biological pathways are driving each individual's cancer, with the goal of matching patients to targeted treatments that may work better for them personally. **You may be eligible if...** - You are a woman over 18 with ovarian cancer that has come back after treatment - Your cancer did not respond to platinum-based chemotherapy (returned within 6 months), or you have chosen not to pursue standard chemotherapy - Your CA125 tumor marker has been rising on two blood tests taken at least 28 days apart - You are willing to have a tumor biopsy taken - You speak and understand Dutch - You are in reasonably good overall health (able to care for yourself) **You may NOT be eligible if...** - You are currently receiving any other cancer treatment - You have never received chemotherapy before - You had a second primary cancer (other than non-melanoma skin cancer) within the past year - You are pregnant or breastfeeding - You are participating in another treatment clinical trial Talk to your doctor to see if this trial is right for you.