Bariatric Surgery and Pharmacokinetics of Irbesartan
Bariatric Surgery and Pharmacokinetics Irbesartan: BAR-MEDS Irbesartan
Norwegian University of Science and Technology
12 participants
Nov 2, 2016
OBSERVATIONAL
Conditions
Summary
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on irbesartan are investigated.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Patients are tested for their normal prescription irbesartan medication
Locations(1)
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NCT03476603