Obesity, Morbid Clinical Trials

69 recruitingLast updated: June 18, 2026

There are 69 actively recruiting obesity, morbid clinical trials across 23 countries. Studies span Not Applicable, Phase 4, Early Phase 1, Phase 2, Phase 3. Top locations include Trondheim, Norway, Chicago, Illinois, United States, Québec, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Obesity, Morbid Trials at a Glance

69 actively recruiting trials for obesity, morbid are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 28 trials, with the heaviest enrollment activity in Trondheim, Chicago, and Québec. Lead sponsors running obesity, morbid studies include Norwegian University of Science and Technology, Istituto Auxologico Italiano, and Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

Browse obesity, morbid trials by phase

Treatments under study

About Obesity, Morbid Clinical Trials

Looking for clinical trials for Obesity, Morbid? There are currently 69 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Obesity, Morbid trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Obesity, Morbid clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 69 trials

Recruiting
Not Applicable

Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery

Obesity and OverweightBariatric SurgeryObesity, Morbid+4 more
Centre Hospitalier Metropole Savoie165 enrolled1 locationNCT06951893
Recruiting

Flow-Controlled vs Volume-Controlled Ventilation in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery

Mechanical VentilationObesity, MorbidBariatric Surgery (Sleeve Gastrectomy )
Ankara Training and Research Hospital34 enrolled1 locationNCT07641829
Recruiting
Not Applicable

Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity

Obesity, Morbid
Oslo University Hospital220 enrolled2 locationsNCT05611697
Recruiting

Periodontal Microbiota of Patients Candidates for Bariatric Surgery With Body Mass Index Greater Than 30

Bariatric SurgeryObesity, Morbid
University Hospital, Toulouse170 enrolled1 locationNCT06781229
Recruiting
Not Applicable

DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass

Weight GainObesity, Morbid
St. Antonius Hospital150 enrolled8 locationsNCT04894838
Recruiting
Phase 4

Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System

AnesthesiaObesity, MorbidPropofol
Sir Ganga Ram Hospital46 enrolled1 locationNCT05305313
Recruiting
Not Applicable

Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study.

ARDS, HumanObesity, Morbid
Assistance Publique - Hôpitaux de Paris40 enrolled5 locationsNCT06119516
Recruiting
Not Applicable

Metabolic Effects of a Diet Replaced With Essential Amino Acids

Weight LossObesity, Morbid
Istituto Auxologico Italiano60 enrolled1 locationNCT06309563
Recruiting
Not Applicable

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

Obesity, Morbid
Mayo Clinic30 enrolled1 locationNCT03868592
Recruiting
Not Applicable

Trans-nasal Endoscopy for Bariatric Patients

ObesityGastrointestinal DiseasesObese+2 more
Christopher C. Thompson, MD, MSc100 enrolled1 locationNCT06200961
Recruiting

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

ObesityMetabolic DiseaseDelayed Gastric Emptying Following Procedure+2 more
Christopher C. Thompson, MD, MSc30 enrolled1 locationNCT05711758
Recruiting

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Obesity, MorbidNASH - Nonalcoholic SteatohepatitisChronic Inflammation
Mayo Clinic60 enrolled1 locationNCT04232566
Recruiting
Not Applicable

Time-restricted Eating Among Pregnant Females With Severe Obesity

Time Restricted EatingObesity, MorbidPregnancy weight gain
University of Illinois at Chicago60 enrolled1 locationNCT06477120
Recruiting
Not Applicable

Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery

ObesityObesity, Morbid
Laval University151 enrolled1 locationNCT05242835
Recruiting
Not Applicable

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

extubation failureObesity, Morbid
Rush University Medical Center250 enrolled5 locationsNCT05918575
Recruiting
Not Applicable

Bariatric Surgery and Modulation of Perceived Satiety

Obesity, Morbid
Istituto Auxologico Italiano60 enrolled1 locationNCT05777928
Recruiting
Early Phase 1

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

ObesityMultiple SclerosisLong COVID+4 more
University of Chicago30 enrolled1 locationNCT06171152
Recruiting
Not Applicable

Low Impact Laparoscopy In Bariatric Surgery

Obesity, Morbid
Fondazione Policlinico Universitario Campus Bio-Medico128 enrolled1 locationNCT07119437
Recruiting
Phase 4

Improving Efficacity of Sleeve Gastrectomy With Naltrexone/Bupropion Extended-release Tablet

Obesity, MorbidObesity; Drug
Laval University108 enrolled1 locationNCT06620562
Recruiting
Phase 4

Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery

Bariatric SurgeryObesity, MorbidHemorrhage
Patel Hospital, Pakistan140 enrolled1 locationNCT07098780