Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients

This trial is testing a new imaging agent called [68Ga]CBP8 — a substance given by injection that shows up on a PET scan and highlights areas of scar tissue (collagen buildup) in the lungs — in healthy people, lung cancer patients, and people with pulmonary fibrosis or lung transplant complications. **You may be eligible if...** - You are 18 years or older (or 40–80 for lung fibrosis and transplant groups) - You are a healthy non-smoker with no history of lung disease, OR - You have locally advanced non-small cell lung cancer (stage IIIA) and are a candidate for combined treatment and surgery, OR - You have pulmonary fibrosis (scarring of the lungs) or another fibrotic lung disease, OR - You have received a lung transplant and are experiencing chronic rejection or airway complications - You have not smoked within the past 6 months (lung cancer and fibrosis/transplant groups) **You may NOT be eligible if...** - You are a current or recent smoker (in most groups) - You have a history of lung disease (healthy group) - You do not fit into one of the four study groups listed above Talk to your doctor to see if this trial is right for you.