Imaging Histone Deacetylase in the Heart

This study uses special imaging scans to look at how certain proteins in the heart change in people with diabetes or a narrowing of the heart valve (aortic stenosis), compared to healthy people. **You may be eligible if...** - You are between 18 and 85 years old - You are a healthy adult with no history of medical or heart conditions (Group 1), OR - You have been diagnosed with diabetes and had a heart ultrasound in the last year that showed no thickening of the heart wall (Group 2), OR - You have been diagnosed with aortic stenosis (a narrowed heart valve) with a thickened heart wall, confirmed by ultrasound or MRI in the last year (Group 3) - You are able to give informed consent **You may NOT be eligible if...** - You have a known reason you cannot have an MRI scan (such as a pacemaker or certain metal implants) Talk to your doctor to see if this trial is right for you.