Aortic Valve Stenosis Clinical Trials

71 recruiting

Aortic Valve Stenosis Trials at a Glance

82 actively recruiting trials for aortic valve stenosis are listed on ClinicalTrialsFinder across 6 cities in 37 countries. The largest study group is Not Applicable with 37 trials, with the heaviest enrollment activity in Milan, San Francisco, and Madrid. Lead sponsors running aortic valve stenosis studies include St. Antonius Hospital, Institut universitaire de cardiologie et de pneumologie de Québec, University Laval, and IRCCS Policlinico S. Donato.

Browse aortic valve stenosis trials by phase

Treatments under study

About Aortic Valve Stenosis Clinical Trials

Looking for clinical trials for Aortic Valve Stenosis? There are currently 71 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Aortic Valve Stenosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Aortic Valve Stenosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 82 trials

Recruiting

Hydra Registry - Italy Experience

Aortic Valve Stenosis
Sahajanand Medical Technologies Limited500 enrolled4 locationsNCT05956652
Recruiting
Phase 4

Patient Quality of Recovery After TAVR With Different Sedation Regimens

Aortic Valve StenosisTranscatheter Aortic Valve Replacement (TAVR)
David Lyubashevsky126 enrolled1 locationNCT07556523
Recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis
Sahajanand Medical Technologies Limited50 enrolled1 locationNCT06342635
Recruiting

Hydra Registry - UK

Aortic Valve Stenosis
Sahajanand Medical Technologies Limited250 enrolled4 locationsNCT06507579
Recruiting

Ischemic And Bleeding Risk Assessment After TAVR

Aortic Valve StenosisTranscatheter Aortic Valve Replacement
Niguarda Hospital2,500 enrolled12 locationsNCT06000943
Recruiting

COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)

Aortic Valve StenosisTranscatheter Aortic Valve Replacement
Niguarda Hospital100 enrolled1 locationNCT05779787
Recruiting

Detecting Changes in Arterial Blood Volume and Cardiac Efficiency

Aortic Valve Stenosis
HemoCept Inc.20 enrolled1 locationNCT07205341
Recruiting
Phase 2Phase 3

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

Moderate Aortic Valve Stenosis
Kardigan, Inc.1,276 enrolled70 locationsNCT07001800
Recruiting

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust550 enrolled61 locationsNCT06557798
Recruiting
Not Applicable

MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)

Coronary Artery DiseaseAortic Valve StenosisExtracorporeal Circulation; Complications
Aristotle University Of Thessaloniki1,300 enrolled13 locationsNCT05487612
Recruiting
Not Applicable

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Aortic Valve StenosisAortic Valve RegurgitationProsthesis Failure
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval310 enrolled7 locationsNCT05459233
Recruiting

Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.

Aortic Valve StenosisTranscatheter Aortic Valve Replacement
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval150 enrolled1 locationNCT06420830
Recruiting
Not Applicable

Post-Dilatation Effect on TAVI Prostheses Expansion

Aortic Valve Stenosis
Medical University of Vienna146 enrolled1 locationNCT07477002
Recruiting
Not Applicable

Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging

Aortic Valve StenosisLeft Ventricle FunctionTranscatheter Aortic Valve Replacement (TAVR)
IRCCS Policlinico S. Donato190 enrolled2 locationsNCT07455292
Recruiting
Not Applicable

Remote Cardiovascular Monitoring in Post-TAVI Patients

Digital HealthTAVIAortic Valve Stenosis+2 more
Imperial College London216 enrolled1 locationNCT06602609
Recruiting
Phase 4

Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation

Aortic Valve Stenosis
Erasmus Medical Center402 enrolled1 locationNCT07370688
Recruiting

Portuguese Registry With Meril Myval THV Series - MyPORTuVal Registry

Aortic Valve StenosisTAVI(Transcatheter Aortic Valve Implantation)
Portuguese Association of Interventional Cardiology150 enrolled6 locationsNCT06818435
Recruiting
Not Applicable

A Clinical Study Using FAPI-PET Imaging to Assess the Postoperative Effects of TAVI in Patients With Aortic Stenosis

Severe Aortic Valve Stenosis
RenJi Hospital25 enrolled1 locationNCT07335900
Recruiting

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

Aortic Valve StenosisIliac Disease
Baylor Research Institute50 enrolled1 locationNCT05862558
Recruiting

VitaFlow LIBERTY Europe

Aortic Valve Stenosis
Shanghai MicroPort CardioFlow Medtech Co., Ltd.122 enrolled6 locationsNCT06535659