Aortic Valve Stenosis Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about Aortic Valve Stenosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging

Aortic Valve StenosisLeft Ventricle FunctionTranscatheter Aortic Valve Replacement (TAVR)
IRCCS Policlinico S. Donato190 enrolled2 locationsNCT07455292
Recruiting

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust550 enrolled53 locationsNCT06557798
Recruiting
Not Applicable

Imaging Histone Deacetylase in the Heart

DiabetesAortic Valve StenosisHeart Failure With Normal Ejection Fraction+1 more
Massachusetts General Hospital96 enrolled1 locationNCT03549559
Recruiting
Phase 4

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement

Heart FailureAortic Valve Stenosis
Duk-Woo Park, MD1,040 enrolled31 locationsNCT05672836
Recruiting
Not Applicable

TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

Aortic Valve DiseaseProsthesis DurabilityAortic Valve Stenosis+6 more
Heinrich-Heine University, Duesseldorf100 enrolled1 locationNCT06896227
Recruiting

Prospective Observational Cohort Study of Moderate Aortic Valve Disease

Aortic Valve DiseaseModerate Aortic Valve StenosisModerate Aortic Valve Regurgitation
Second Affiliated Hospital, School of Medicine, Zhejiang University1,000 enrolled1 locationNCT06595992
Recruiting
Not Applicable

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Aortic Valve StenosisAortic Valve RegurgitationProsthesis Failure
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval310 enrolled7 locationsNCT05459233
Recruiting
Not Applicable

Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation

Severe Aortic Valve Stenosis
St. Antonius Hospital2,500 enrolled1 locationNCT06168370
Recruiting
Not Applicable

Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis

Heart FailureAortic Valve StenosisHypertension,Essential
Henrik Wiggers200 enrolled6 locationsNCT04613193