RecruitingPhase 3NCT03559114

PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)

PROTEST Trial - PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury, a Double-blind Randomized Controlled Trial

Sponsor

Sunnybrook Health Sciences Centre

Enrollment

1,100 participants

Start Date

Jul 19, 2018

Study Type

INTERVENTIONAL

Conditions

Traumatic Brain Injury

Summary

This is a phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dalteparin and a drug called Saline for people with traumatic brain injury. The study is currently recruiting participants at 12 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDalteparin

Dalteparin in prophylactic doses administered daily if screening criteria are satisfied.

DRUGSaline

Saline in prophylactic doses administered daily if screening criteria are satisfied.

Locations(12)

Foothills Medical Centre

Calgary, Alberta, Canada

Royal Alexandra Hospital

Edmonton, Alberta, Canada

University of Alberta Hospital

Edmonton, Alberta, Canada

Vancouver General Hospital

Vancouver, British Columbia, Canada

Queen Elizabeth II Health Sciences Centre

Halifax, Nova Scotia, Canada

Hamilton Health Sciences Centre

Hamilton, Ontario, Canada

Kingston General Hospital

Kingston, Ontario, Canada

The Ottawa Hospital

Ottawa, Ontario, Canada

Sunnybrook Health Science Centre

Toronto, Ontario, Canada

Unity Health Toronto

Toronto, Ontario, Canada

Hopital de L'Enfant-Jesus

Québec, Quebec, Canada

Royal University Hospital

Saskatoon, Saskatchewan, Canada

View Full Details on ClinicalTrials.gov

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NCT03559114

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