RecruitingNCT03593408

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support


Sponsor

Boston Children's Hospital

Enrollment

20 participants

Start Date

Feb 8, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.


Eligibility

Min Age: 0 DaysMax Age: 17 Years

Inclusion Criteria2

  • supported on ECMO
  • receiving one or a combination of the following drugs dexmedetomidine, fentanyl, midazolam or morphine as part of sedation management

Exclusion Criteria1

  • none

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Interventions

DRUGDexmedetomidine

Administered for sedation management per hospital protocol

DRUGFentanyl

Administered for sedation management per hospital protocol

DRUGMidazolam

Administered for sedation management per hospital protocol

DRUGMorphine

Administered for sedation management per hospital protocol


Locations(1)

Boston Children's Hospital

Boston, Massachusetts, United States

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NCT03593408


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