Vitamin D Homeostasis in Sarcoidosis
University of Texas Southwestern Medical Center
90 participants
Jul 1, 2010
INTERVENTIONAL
Conditions
Summary
This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis. Half the patients with sarcoidosis who are vitamin-D insufficient will receive standard vitamin-D supplementation via standard regimen while the other half will receive a placebo. Sarcoidosis patients who are vitamin-D sufficient will also act as controls.
Eligibility
Inclusion Criteria5
- Stable medical condition defined as no hospitalization or emergency room visit in the previous 3 months
- No evidence of active pulmonary or systemic infection
- No other active inflammatory disease,
- No active malignancy.
- Normal serum ionized calcium level
Exclusion Criteria5
- Hospitalization or emergency room visit in the previous 3 months
- Evidence of active pulmonary or systemic infection
- Evidence of active other inflammatory disease
- Evidence of active malignancy
- Elevated serum ionized calcium level
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Interventions
Vitamin D2 50,000 units
Sugar pill manufactured to mimic ergocalciferol 50,000 units
To meet the recommended minimum daily dietary requirements
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03621553