RecruitingNCT03621904

PROMOTE Study: Prediction of Response Of HorMOnal Treatment in Advanced and Recurrent Endometrial Cancer


Sponsor

Radboud University Medical Center

Enrollment

150 participants

Start Date

Oct 15, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The PROMOTE study aims at optimising use of hormonal therapy in advanced stage and recurrent endometrial cancer analysing tumor tissue taken before start of hormonal therapy


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 110 Years

Inclusion Criteria4

  • Advanced stage (FIGO stage III and IV) and recurrent endometrial cancer
  • All histologic types of endometrial carcinoma
  • Planned treatment with any type of hormonal therapy
  • Biopsy taken within 120 days prior to start of hormonal therapy with no intercurrent therapy between biopsy and start of hormonal therapy.

Exclusion Criteria3

  • Adjuvant hormonal therapy started following complete resection of endometrial carcinoma
  • Synchronous use of hormonal therapy for other indications
  • Endometrial sarcoma or endometrial stroma cell sarcoma

Interventions

DRUGHormonal Antineoplastics

Hormonal therapy used for treatment in endometrial cancer patients


Locations(1)

Radboudumc

Nijmegen, Netherlands

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NCT03621904


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