RecruitingNCT03626233

Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

Study of the Physiology of Pre-eclampsia and Vascular Intrauterine Growth Restriction With Constitution of a Biological Collection


Sponsor

Centre Hospitalier Intercommunal Creteil

Enrollment

500 participants

Start Date

Aug 6, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • pregnant women
  • With or without vascular pathology

Exclusion Criteria3

  • refusal to participate
  • multiple pregnancy
  • major fetal malformation diagnosed during pregnancy follow-up

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Interventions

OTHERcollect of placenta, blood and urinary samples at delivery

collect of placenta, blood and urinary samples at delivery


Locations(1)

CHi Creteil

Créteil, France

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NCT03626233


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