Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection
Study of the Physiology of Pre-eclampsia and Vascular Intrauterine Growth Restriction With Constitution of a Biological Collection
Centre Hospitalier Intercommunal Creteil
500 participants
Aug 6, 2018
OBSERVATIONAL
Conditions
Summary
Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal
Eligibility
Inclusion Criteria2
- pregnant women
- With or without vascular pathology
Exclusion Criteria3
- refusal to participate
- multiple pregnancy
- major fetal malformation diagnosed during pregnancy follow-up
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Interventions
collect of placenta, blood and urinary samples at delivery
Locations(1)
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NCT03626233