Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

This trial is testing whether deep transcranial magnetic stimulation (Deep TMS) — a non-invasive brain stimulation technique that uses magnetic pulses — can improve both depression and memory/thinking problems in older adults who have both Alzheimer's disease and major depression. **You may be eligible if...** - You have been diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease (with a CDR score of at least 0.5) - You have also been diagnosed with major depression lasting more than 4 weeks but less than 5 years - You have not responded to or could not tolerate antidepressant medications - You are willing to provide informed consent (you or a caregiver) **You may NOT be eligible if...** - You have metal implants in or near your head (e.g., clips, stents, cochlear implants) that are unsafe with magnetic stimulation - You have a history of seizures or epilepsy - You are taking medications that significantly lower the seizure threshold - You have severe dementia or very advanced Alzheimer's - You have other major psychiatric diagnoses - You are currently taking antidepressants that have not been tried long enough Talk to your doctor to see if this trial is right for you.