RecruitingNCT03676647

Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

Retrospective-Prospective Collection of Thyroid Specimens After FNA


Sponsor

City of Hope Medical Center

Enrollment

22 participants

Start Date

Apr 25, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.


Eligibility

Min Age: 19 Years

Inclusion Criteria3

  • All patients undergoing FNA for thyroid nodule diagnosis.
  • Any race and ethnicity are eligible for the study.
  • Patient should have thyroid nodule(s) with indeterminate diagnosis after FNA (Bethesda category of indeterminate FNA \[III-V\]).

Interventions

OTHERDiagnostic DNA Methylation Signature

Undergo collection of tissue samples


Locations(1)

City of Hope Medical Center

Duarte, California, United States

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NCT03676647


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