RecruitingNCT04742608

Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

Isolation and Characterization of Extracellular Vesicles in Patients With Thyroid Nodules and Thyroid Cancer

Sponsor

Jonsson Comprehensive Cancer Center

Enrollment

250 participants

Start Date

Feb 21, 2020

Study Type

OBSERVATIONAL

Conditions

Thyroid Gland Carcinoma Thyroid Gland Nodule

Summary

This study is being done to help researchers learn more about and successfully diagnose cancer using blood samples and tissue samples from surgeries in patients with suspicious thyroid nodules or thyroid cancer. Diagnosing cancer in this way, as opposed to biopsies, may be less invasive to the patient. Analyzing blood and tissues samples may also help researchers to differentiate non-cancerous tumors from thyroid cancer and detect high-risk mutations to guide treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study develops and validates blood-based tests (liquid biopsies) that can detect thyroid cancer or assess whether a thyroid nodule is cancerous — without needing to rely solely on surgery or tissue biopsies. **You may be eligible if...** - You are 18 years or older - You have a thyroid nodule that is being assessed for possible cancer or a confirmed thyroid cancer diagnosis - You have already agreed to undergo thyroid surgery **You may NOT be eligible if...** - You have another active cancer that could confound the results - You are not scheduled for thyroid surgery - You are under 18 years of age Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo collection of blood and tissue samples

OTHERElectronic Health Record Review

Medical charts are reviewed

Locations(1)

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, United States

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NCT04742608

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