RecruitingNot ApplicableNCT03683680

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers


Sponsor

Dana-Farber Cancer Institute

Enrollment

240 participants

Start Date

Oct 31, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

This research study is evaluating a new method for determining stage and prognosis of individuals with malignant pleural mesothelioma.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting tissue samples from patients with malignant pleural mesothelioma (a rare cancer of the lining of the lungs, often linked to asbestos exposure) to test biological markers that may help doctors predict how the disease will progress and how patients will respond to treatment. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with malignant pleural mesothelioma - You are scheduled for a diagnostic biopsy, pleuroscopy (a procedure to look inside the chest), or surgery to remove tissue **You may NOT be eligible if...** - You have been assessed as not suitable for surgery, diagnosis, or treatment - You are considered too unwell to undergo the planned procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMPT Test

molecular expression tests at the RNA level using approximately 7 or more genes with RTPCR, nanostring or similar platforms

OTHERCLDN15/VIM Test

molecular expression tests at the RNA level using approximately 7 or more genes with RTPCR, nanostring or similar platforms


Locations(1)

Brigham and Women's Hospital

Boston, Massachusetts, United States

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NCT03683680


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