RecruitingNot ApplicableNCT03684109

Non-invasive Glioma Characterization Through Molecular Imaging

Pilot Study for Non-invasive Glioma Characterization Through Molecular Imaging


Sponsor

University of Miami

Enrollment

30 participants

Start Date

Jan 25, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using a special type of brain scan (combining PET and MRI imaging) to better understand the biology of gliomas (a type of brain tumor) before surgery, with the goal of helping doctors diagnose and treat these tumors more accurately without needing to rely solely on tissue samples. **You may be eligible if...** - You are 18 years or older - You have a suspected or confirmed glioma (brain tumor) - You are already scheduled for a medically necessary biopsy or surgery to remove or sample your brain tumor **You may NOT be eligible if...** - You cannot give your own informed consent - You are under 18 years old - You are pregnant - You cannot have an MRI scan (for example, if you have a pacemaker or are severely claustrophobic) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICE3T MRI Scanner

3T MRI Scanner providing Mega-laser sequence for single-voxel Magnetic Resonance Spectroscopy (MRS) data for 2 hydroxyglutarate (2HG) quantitation.


Locations(1)

University of Miami

Miami, Florida, United States

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NCT03684109


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