RecruitingNot ApplicableNCT03726047

Exercise and Motor Learning After Stroke (Study #3)

Feedback and Cognition During Locomotor Learning Post Stroke


Sponsor

University of Delaware

Enrollment

80 participants

Start Date

Dec 1, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

Subjects with chronic stroke (\> 6 months post-stroke) will learn a new walking pattern through distorted visual feedback. Retention of the pattern will be tested without visual feedback immediately after learning and 24 hours later. Subjects will be randomly assigned to the control group or the exercise group. The control group will simply complete the learning task. The exercise group will complete 5 minutes of exercise immediately following the first retention test to test for the effects of exercise on retention 24 hours later.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether a bout of aerobic exercise before a motor learning task helps stroke survivors relearn movement more effectively. After a stroke, people often have difficulty performing everyday movements due to damage in the brain. Research has shown that exercise can boost the brain's plasticity — its ability to reorganize and form new connections. This study tests whether that exercise-induced boost can speed up or improve motor skill relearning in people who had a stroke more than 6 months ago. Participants will complete exercise sessions and motor learning tasks over several visits, with researchers tracking both movement performance and physiological responses. There is no medication involved. The study builds on earlier phases and focuses specifically on walking-related motor tasks. Findings could directly improve rehabilitation programs for stroke survivors. You may be eligible if: - You are 18–85 years old - You had a single stroke more than 6 months ago, confirmed by MRI or CT - You can walk at your own pace without another person's help - Your resting heart rate is between 40–100 bpm and blood pressure is within a safe range You may NOT be eligible if: - Your stroke affected the cerebellum - You had a heart attack or bypass surgery in the past 3 months - You have another neurological condition in addition to your stroke - You have visual field loss or neglect - You experience unexplained dizziness in the last 6 months - You have musculoskeletal pain that limits walking Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExercise

Subjects will complete 5 minutes of exercise on an ergometer to examine the effects of exercise on retention of a newly learned walking pattern.


Locations(1)

University of Delaware

Newark, Delaware, United States

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NCT03726047


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