RecruitingNot ApplicableNCT03749538

Acute Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies


Sponsor

University of Sao Paulo

Enrollment

40 participants

Start Date

Oct 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

Systemic autoimmune myopathies are a heterogeneous group of rheumatic diseases that primarily affect the skeletal muscles. The transcranial direct current stimulation technique has been frequent, for example, in patients with ischemic stroke or for the optimization of muscular performance in athletes. However, to date, there are no studies evaluating this technique in patients with systemic autoimmune myopathies. Therefore, the main objective of the present prospective, randomized, double-blind, placebo-controlled study is to evaluate the safety and efficacy of the application of acute transcranial current stimulation session in patients with systemic autoimmune myopathies.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This Brazilian study is investigating whether transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation technique — can help improve muscle weakness in patients with systemic autoimmune myopathies (inflammatory muscle diseases). tDCS delivers a mild electrical current to the scalp and may help the nervous system function better in people with these conditions. You may be eligible if: - You have been diagnosed with a systemic autoimmune myopathy (classified by EULAR/ACR 2017 or Connors criteria) - You have objective limb muscle weakness - You are between 18 and 80 years old You may NOT be eligible if: - You have an active cancer (neoplasia) - You use a heart pacemaker - You have visceral metallic clips - You have active infections (HIV, HTLV-1, hepatitis, etc.) - You are pregnant - You have a history of seizures or epilepsy Talk to your rheumatologist or neurologist about whether your autoimmune muscle disease and overall health make you a candidate for brain stimulation therapy research.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTranscranial direct current stimulation session.

Patients with systemic autoimmune myopathies will receive or not acute transcranial direct current stimulation session.


Locations(1)

Samuel K Shinjo

São Paulo, Brazil

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NCT03749538


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