Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

This trial is comparing whether giving focused brain radiation (stereotactic radiosurgery, or SRS) before or after surgery leads to better outcomes for patients who need an operation to remove a brain metastasis (cancer that has spread to the brain). **You may be eligible if...** - You are 18 years or older - You have cancer that has spread to the brain and surgery is recommended to remove one tumor - Your overall health is reasonably good (ECOG performance status acceptable) - You have 10 or fewer brain tumors total that need radiation - Your tumor type is a solid cancer (not lymphoma or other blood cancers) **You may NOT be eligible if...** - You have more than 10 brain tumors requiring treatment - Your overall health is too poor for surgery or radiation - You are pregnant - You have cancer that has spread throughout the lining of the brain (leptomeningeal disease) Talk to your doctor to see if this trial is right for you.