RecruitingPhase 3NCT03789916

SAPT Versus DAPT in Incomplete Revascularization After CABG

Single Versus Dual Antiplatelet Therapy in Patients With Incomplete Revascularization After Coronary Artery Bypass Graft Surgery


Sponsor

Campus Bio-Medico University

Enrollment

800 participants

Start Date

Jan 2, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The study aims to compare the efficacy of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients with incomplete revascularization after coronary artery bypass graft surgery (CABG). Before hospital discharge, patients will be 1:1 randomized to SAPT (acetylsalicylic acid 100 mg/die) or DAPT (acetylsalicylic acid 100 mg/die + ticagrelor 90 mg bis in die). DAPT will be continued for 12 months, and ticagrelor will be withdrawn thereafter. Primary endpoint is the evaluation of cardiac-related mortality at 5 years from hospital discharge.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Ticagrelor and a drug called acetylsalicylic acid for people with coronary artery disease. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTicagrelor

90 mg bis in die

DRUGacetylsalicylic acid

100 mg die


Locations(1)

Università Campus Bio-Medico di Roma

Rome, Italy

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NCT03789916


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