Efficacy of Nitrous Oxide in OCD: Pilot Study

This pilot (small, early-stage) trial is studying whether nitrous oxide (commonly known as "laughing gas," used safely in medicine and dentistry for decades) given in controlled doses can reduce the symptoms of obsessive-compulsive disorder (OCD) — a condition involving repeated unwanted thoughts and compulsive behaviors. **You may be eligible if...** - You are between 18 and 65 years old - You have a primary diagnosis of OCD - Your OCD symptoms are severe enough to qualify - You are able to go without OCD treatment for a short period during the study - You are capable of giving informed consent **You may NOT be eligible if...** - You have a psychiatric or medical condition that would make it unsafe to receive nitrous oxide - You are pregnant or nursing - You are taking medications that could have dangerous interactions with nitrous oxide Talk to your doctor to see if this trial is right for you.