Obsessive-Compulsive Disorder Clinical Trials

81 recruiting

Frequently Asked Questions

Common questions about Obsessive-Compulsive Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 81 trials

Recruiting

A Multicenter Pediatric Deep Brain Stimulation Registry

Movement DisordersNeurologic DisorderCerebral Palsy+6 more
Boston Children's Hospital100 enrolled1 locationNCT06585618
Recruiting
Phase 1Phase 2

Pilot Study of RR-HNK in OCD

Obsessive-Compulsive Disorder
Carolyn Rodriguez45 enrolled1 locationNCT06575075
Recruiting
Phase 2

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Obsessive-Compulsive Disorder
Carolyn Rodriguez40 enrolled1 locationNCT05783817
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting

University of Iowa Interventional Psychiatry Service Patient Registry

Major Depressive DisorderMajor DepressionObsessive-Compulsive Disorder+4 more
Mark Niciu1,000 enrolled1 locationNCT04480918
Recruiting

Developing Brain, Impulsivity and Compulsivity

Autism Spectrum DisorderAttention Deficit Hyperactivity DisorderObsessive-Compulsive Disorder+2 more
National Institute of Mental Health (NIMH)1,100 enrolled1 locationNCT04631042
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
University of Texas at Austin600 enrolled2 locationsNCT05467683
Recruiting
Phase 1

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Obsessive-Compulsive Disorder
Francisco A Moreno30 enrolled1 locationNCT07347405
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable

Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders

Obsessive-Compulsive DisorderIllness Anxiety DisorderBody Dysmorphic Disorders
Stanford University16 enrolled1 locationNCT03918577
Recruiting
Not Applicable

Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Centre Hospitalier Henri Laborit136 enrolled2 locationsNCT04934007
Recruiting
Not Applicable

SEEG-Guided DBS for OCD

Obsessive-Compulsive Disorder
Casey H. Halpern, M.D.10 enrolled2 locationsNCT05623306
Recruiting
Not Applicable

Mechanisms of Exposure Therapy for OCD

Obsessive-Compulsive Disorder
Mclean Hospital400 enrolled2 locationsNCT06173752
Recruiting
Not Applicable

Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients

Obsessive-Compulsive DisorderVirtual Reality Exposure TherapyVirtual Reality Cognitive Training+1 more
National Institute of Mental Health, Czech Republic62 enrolled1 locationNCT07245134
Recruiting
Phase 2

Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD

Obsessive-Compulsive Disorder
Beersheva Mental Health Center15 enrolled1 locationNCT04882839
Recruiting
Not Applicable

Brief Culturally Adapted CBT for OCD

Obsessive-Compulsive DisorderCognitive Behavioral Therapy
Pakistan Association of Cognitive Therapists166 enrolled1 locationNCT07232823
Recruiting
Early Phase 1

Effects of Psilocybin in Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Johns Hopkins University30 enrolled1 locationNCT05546658
Recruiting
Not Applicable

Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder
Adam Frank48 enrolled1 locationNCT07146438
Recruiting
Not Applicable

Precision Analytic Research Methods in OCD

Obsessive-Compulsive Disorder
Icahn School of Medicine at Mount Sinai100 enrolled1 locationNCT07011901
Recruiting
Not Applicable

Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial

Obsessive-Compulsive Disorder
National Institute of Mental Health, Czech Republic30 enrolled1 locationNCT07206199