Obsessive-Compulsive Disorder Clinical Trials

80 recruiting

Obsessive-Compulsive Disorder Trials at a Glance

76 actively recruiting trials for obsessive-compulsive disorder are listed on ClinicalTrialsFinder across 6 cities in 20 countries. The largest study group is Not Applicable with 48 trials, with the heaviest enrollment activity in Stanford, San Francisco, and Boston. Lead sponsors running obsessive-compulsive disorder studies include Stanford University, Mclean Hospital, and Carolyn Rodriguez.

Browse obsessive-compulsive disorder trials by phase

Treatments under study

About Obsessive-Compulsive Disorder Clinical Trials

Looking for clinical trials for Obsessive-Compulsive Disorder? There are currently 80 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Obsessive-Compulsive Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Obsessive-Compulsive Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 76 trials

Recruiting
Not Applicable

Cortical Stimulation to Treat Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Andrew Moses Lee, MD, PhD15 enrolled1 locationNCT04958096
Recruiting
Phase 2

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Obsessive-Compulsive Disorder
Stanford University150 enrolled1 locationNCT05940324
Recruiting
Not Applicable

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Depressive DisorderAnxiety DisordersObsessive-Compulsive Disorder+1 more
Peking University464 enrolled1 locationNCT07458100
Recruiting

Retrospective Analyses of TrakStar Database

Anxiety DepressionDepressionObsessive-Compulsive Disorder
Neuronetics156,000 enrolled1 locationNCT06917339
Recruiting
Not Applicable

SEEG-Guided DBS for OCD

Obsessive-Compulsive Disorder
Katherine Scangos10 enrolled2 locationsNCT05623306
Recruiting
Phase 1

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Obsessive-Compulsive Disorder
Centre for Addiction and Mental Health10 enrolled1 locationNCT06299319
Recruiting

A Multicenter Pediatric Deep Brain Stimulation Registry

Movement DisordersNeurologic DisorderCerebral Palsy+6 more
Boston Children's Hospital100 enrolled1 locationNCT06585618
Recruiting
Phase 1Phase 2

Pilot Study of RR-HNK in OCD

Obsessive-Compulsive Disorder
Carolyn Rodriguez45 enrolled1 locationNCT06575075
Recruiting
Phase 2

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Obsessive-Compulsive Disorder
Carolyn Rodriguez40 enrolled1 locationNCT05783817
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting

University of Iowa Interventional Psychiatry Service Patient Registry

Major Depressive DisorderMajor DepressionObsessive-Compulsive Disorder+4 more
Mark Niciu1,000 enrolled1 locationNCT04480918
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
University of Texas at Austin600 enrolled2 locationsNCT05467683
Recruiting
Phase 1

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Obsessive-Compulsive Disorder
Francisco A Moreno30 enrolled1 locationNCT07347405
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable

Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders

Obsessive-Compulsive DisorderIllness Anxiety DisorderBody Dysmorphic Disorders
Stanford University16 enrolled1 locationNCT03918577
Recruiting
Not Applicable

Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Centre Hospitalier Henri Laborit136 enrolled2 locationsNCT04934007
Recruiting
Not Applicable

Mechanisms of Exposure Therapy for OCD

Obsessive-Compulsive Disorder
Mclean Hospital400 enrolled2 locationsNCT06173752
Recruiting
Not Applicable

Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients

Obsessive-Compulsive DisorderVirtual Reality Exposure TherapyVirtual Reality Cognitive Training+1 more
National Institute of Mental Health, Czech Republic62 enrolled1 locationNCT07245134
Recruiting
Not Applicable

Brief Culturally Adapted CBT for OCD

Obsessive-Compulsive DisorderCognitive Behavioral Therapy
Pakistan Association of Cognitive Therapists166 enrolled1 locationNCT07232823
Recruiting
Early Phase 1

Effects of Psilocybin in Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Johns Hopkins University30 enrolled1 locationNCT05546658