Obsessive-Compulsive Disorder Clinical Trials

95 recruitingLast updated: June 18, 2026

There are 95 actively recruiting obsessive-compulsive disorder clinical trials across 23 countries. Studies span Not Applicable, Phase 2, Phase 1, Early Phase 1. Top locations include Stanford, California, United States, Shanghai, Shanghai Municipality, China, San Francisco, California, United States. Updated daily from ClinicalTrials.gov.


Obsessive-Compulsive Disorder Trials at a Glance

95 actively recruiting trials for obsessive-compulsive disorder are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 62 trials, with the heaviest enrollment activity in Stanford, Shanghai, and San Francisco. Lead sponsors running obsessive-compulsive disorder studies include Stanford University, Shanghai Mental Health Center, and Mclean Hospital.

Browse obsessive-compulsive disorder trials by phase

Treatments under study

About Obsessive-Compulsive Disorder Clinical Trials

Looking for clinical trials for Obsessive-Compulsive Disorder? There are currently 99 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Obsessive-Compulsive Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Obsessive-Compulsive Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 95 trials

Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
Jasper A. Smits600 enrolled2 locationsNCT05467683
Recruiting
Not Applicable

Project EMPOWER-OCD

Obsessive-Compulsive Disorder
Boston University Charles River Campus110 enrolled1 locationNCT07158801
Recruiting
Not Applicable

Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity

Obsessive-Compulsive DisorderOCD
Mehmet Emrah Karadere36 enrolled1 locationNCT07622654
Recruiting
Phase 2

Study of Dextromethorphan in OCD and Related Disorders

Obsessive-Compulsive DisorderSomatic Symptom DisorderIllness Anxiety Disorder+1 more
Stanford University60 enrolled1 locationNCT04899687
Recruiting
Not Applicable

Interpretation Bias as a Mechanism of Treatment Response in OCD

Obsessive-Compulsive Disorder
Mclean Hospital106 enrolled1 locationNCT05224414
Recruiting
Phase 1

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Obsessive-Compulsive Disorder
Francisco A Moreno30 enrolled1 locationNCT07347405
Recruiting
Not Applicable

SEEG-Guided DBS for OCD

Obsessive-Compulsive Disorder
Casey H. Halpern, M.D.12 enrolled2 locationsNCT05623306
Recruiting

Pharmacogenetics of Antidepressant-Induced Disinhibition

Major Depressive DisorderAnxiety DisordersAntidepressant Drug Adverse Reaction+1 more
University of Calgary120 enrolled1 locationNCT03953014
Recruiting
Not Applicable

Using Personalized Assessments in the Treatment of Childhood OCD

Obsessive-Compulsive Disorder
Johns Hopkins University30 enrolled1 locationNCT06407648
Recruiting
Not Applicable

Electrophysiological Biomarkers and Treatment Response to Accelerated Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder

Obsessive-Compulsive DisorderIntermittent Theta Burst StimulationEEG+1 more
Istanbul University - Cerrahpasa30 enrolled1 locationNCT07561528
Recruiting
Not Applicable

A Precision Medicine Approach to Target Engagement for Emotion Regulation

DepressionAnxietyEating Disorders+4 more
Matthew Southward, PhD390 enrolled1 locationNCT05651295
Recruiting
Not Applicable

ICBT for OCD in Children With Autism

Autism Spectrum DisorderObsessive-Compulsive Disorder
Karolinska Institutet220 enrolled3 locationsNCT06582225
Recruiting
Not Applicable

Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder
Nader Pouratian10 enrolled1 locationNCT06660225
Recruiting
Not Applicable

Cortical Stimulation to Treat Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Andrew Moses Lee, MD, PhD15 enrolled1 locationNCT04958096
Recruiting
Phase 2

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Obsessive-Compulsive Disorder
Stanford University150 enrolled1 locationNCT05940324
Recruiting
Not Applicable

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Depressive DisorderPost Traumatic Stress Disorder (PTSD)Eating Disorders+3 more
Peking University464 enrolled1 locationNCT07458100
Recruiting

Developing Brain, Impulsivity and Compulsivity

Autism Spectrum DisorderAttention Deficit Hyperactivity DisorderObsessive-Compulsive Disorder+2 more
National Institute of Mental Health (NIMH)1,100 enrolled1 locationNCT04631042
Recruiting

Retrospective Analyses of TrakStar Database

Anxiety DepressionDepressionObsessive-Compulsive Disorder
Neuronetics156,000 enrolled1 locationNCT06917339
Recruiting

Neurosurgical Outcome Network

DepressionTrigeminal NeuralgiaObsessive-Compulsive Disorder+20 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting
Phase 1

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Obsessive-Compulsive Disorder
Centre for Addiction and Mental Health10 enrolled1 locationNCT06299319