RecruitingPhase 1NCT03827460

Sex Differences in the Response to Abstinence From Alcohol.


Sponsor

Indiana University

Enrollment

160 participants

Start Date

Apr 10, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the present study, the investigators propose to study how men and women respond to abstinence, and whether this information can be used to improve intervention and prevention strategies.


Eligibility

Min Age: 21 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Abstinence from alcohol, a drug called Intravenous Alcohol, and others for people with alcohol use disorder. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 35 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALAbstinence from alcohol

Participants will undergo a laboratory alcohol infusion session that terminates 2 weeks of monitored abstinence from alcohol

BEHAVIORALUsual drinking

Participants will undergo a laboratory alcohol infusion session during a period of usual drinking behavior

DRUGIntravenous Alcohol

During the laboratory alcohol infusion sessions, alcohol is infused through an indwelling catheter.


Locations(1)

University Hospital

Indianapolis, Indiana, United States

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NCT03827460


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