RecruitingNCT03839992

Detection of Unsuspected Small Airways Obstruction in Cystic Fibrosis

The Measurement and Analysis of Maximal Expiratory Flow Volume Loops at Low Lung Volumes in Children With Cystic Fibrosis and Normal Routine Lung Function.


Sponsor

Gelb, Arthur F., M.D.

Enrollment

100 participants

Start Date

Apr 25, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Goal is to physiologically detect unsuspected small airways obstruction in children and adults with treated heterozygous and homozygous cystic fibrosis. Unsuspected refers to normal routine pre bronchodilator spirometry including normal FEV1(L), FVC (L). and FEV1/FVC%. This is a retrospective study.


Eligibility

Min Age: 5 YearsMax Age: 40 Years

Inclusion Criteria1

  • Heterozygote or homozygote patients with cystic fibrosis with normal routine pre bronchodilator spirometry including normal FEV1(L), FVC(L) and FEV1/FVC%.

Exclusion Criteria1

  • \-

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Interventions

DIAGNOSTIC_TESTspirometry

measure spirometry and lung CT


Locations(2)

Arthur F Gelb MD

Lakewood, California, United States

Miller Children's Hospital and Long Beach Medical Center

Long Beach, California, United States

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NCT03839992


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