RecruitingNCT03865914

Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy


Sponsor

Chinese PLA General Hospital

Enrollment

2,000 participants

Start Date

Nov 30, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

With the rapid increase of diabetic nephropathy worldwide, type 2 diabetes mellitus(DM) is the leading cause of end-stage renal disease(ESRD). Pathological types of diabetic kidney disease(DKD) could be mainly divided into diabetic nephropathy(DN)and non-diabetic renal diseases(NDRD). There are no accurate renal biopsy indications and standardized operation procedures for type 2 diabetic nephropathy. The clinical stages of type 2 diabetic nephropathy still referred to the Mogensen stage of type 1 diabetic nephropathy. Thus, our study aim to clarify the differences in clinical phenotype between type 2 DN and type 2 NDRD, analysis the correlation between clinical and pathological features, and offer the criteria for clinical staging and prognosis.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at the relationship between how type 2 diabetic kidney disease appears in lab tests and symptoms versus how it looks under a microscope after a kidney biopsy. Researchers want to better understand the different forms this disease takes to improve diagnosis and care. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with type 2 diabetes - You have signs of kidney problems such as protein in the urine or reduced kidney function - You have already had a kidney biopsy with a complete pathological diagnosis - You are willing to provide signed informed consent **You may NOT be eligible if...** - Your medical history is incomplete - You have another cause of kidney disease not related to diabetes - You have an inherited kidney disease - You have an autoimmune disease - You have a terminal cancer diagnosis with less than 6 months to live - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Chinese PLA General Hospital

Beijing, Beijing Municipality, China

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NCT03865914


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