RecruitingPhase 1NCT03891706

Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid Tumors

An Open, Single-center, Stage I Clinical Study of Individualized Tumor Specific TCR-T Cells in the Treatment of Advanced Solid Tumors.


Sponsor

Guangzhou FineImmune Biotechnology Co., LTD.

Enrollment

30 participants

Start Date

Jan 8, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this study is to evaluate the safety of the tumor-specific TCR-T cells in the treatment of advanced Solid Tumor . The secondary purpose of this study is to preliminarily showed the effect of TCR-T cells in the treatment of advanced Solid Tumor .


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Interleukin-2 and a drug called tumor-specific TCR-T cells for people with solid tumor. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGtumor-specific TCR-T cells

On day 0 and day 14, 0.5-5x10\^9 TCR-T cells will be infused intravenously (IV) over 1 hour,patients may choose to receive more cell infusions if they benefit from the treatment.

DRUGInterleukin-2

Aldesleukin 3,000,000 IU. IV.QD beginning within 24 hours of cell infusion and continuing for up to 5 days .


Locations(1)

Sun Yat-sen University Cancer Center

Guangzhou, Gaungdong, China

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NCT03891706


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