RecruitingNCT03894423
Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
Comprehensive CT Guided Coronary Bypass Graft Surgery
Sponsor
Stanford University
Enrollment
200 participants
Start Date
May 1, 2019
Study Type
OBSERVATIONAL
Conditions
Summary
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Eligibility
Min Age: 40 Years
Inclusion Criteria3
- Planned elective CABG for coronary artery disease.
- CABG is the primary indication for surgery (but may include treatment of mild-moderate valvular disease).
- Age: ≥40 years.
Exclusion Criteria6
- Technical feasibility of the cardiac CT exams: redo-CABG, significant arrhythmia/mal-conduction, congenital conditions, severe valvular disease or cardiomyopathy (to the extent that the CT acquisition is technically challenged), inadequate understanding of the English language (to provide consent or follow instructions during the exams).
- Overall safety: unstable clinical condition (clinical heart failure, unstable angina, myocardial infarction \<1 month prior).
- Radiation risk: pregnancy (cannot be ruled out), body weight \>100kg.
- CT contrast medium-related: known allergy, renal failure
- Vasodilator related: known allergy, bronchial asthma requiring daily use of bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing, systolic blood pressure below 90mmHg, (continued) use of dipyridamole or aminophylline.
- Inability to provide informed consent.
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Locations(3)
View Full Details on ClinicalTrials.gov
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NCT03894423
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