RecruitingPhase 3NCT03902912

Effect of Prednisolone Treatment on Uterine Natural Killer Cells

Effect of Prednisolone Treatment on Uterine Natural Killer Cells and Endometrial Angiogenesis in Recurrent Miscarriage Around the Time of Embryo Implantation

Sponsor

Chinese University of Hong Kong

Enrollment

84 participants

Start Date

Jul 30, 2019

Study Type

INTERVENTIONAL

Conditions

Recurrent miscarriage

Summary

This study aims to investigate the role of uNK cells and the association with prednisolone.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Prednisolone for people with recurrent miscarriage. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPrednisolone

prednisolone oral 10 mg/day from day one of the subsequent menstrual cycle to day LH 7 of that cycle. Then, the participants will be given a tailing off dose of 5 mg/day for 3 days followed by 2 mg/day for 3 days and then 1 mg/day for 3 days.