RecruitingPhase 2Phase 3NCT03916978
Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women
Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in Menopausal Women
Sponsor
Genesis Athens Clinic
Enrollment
100 participants
Start Date
May 21, 2019
Study Type
INTERVENTIONAL
Conditions
Summary
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.
Eligibility
Sex: FEMALEMin Age: 45 YearsMax Age: 55 Years
Inclusion Criteria4
- Age between 45-55 years old
- Amenorrhea for at least 12 months
- Discontinuation of any complementary/adjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.
- Willing to comply with study requirements
Exclusion Criteria15
- Any pathological disorder related to reproductive system anatomy
- Previous POI diagnosis
- Abnormal karyotype
- Endometriosis
- Adenomyosis
- Fibroids and adhesions
- Infections in reproductive system
- Current or previous diagnosis of reproductive system cancer
- History of familiar cancer in reproductive system
- Severe male factor infertility
- Prior referral for PGT
- Ovarian inaccessibility
- Endocrinological disorders (Hypothalamus-Pituitary disorders, thyroid dysfunction, diabetes mellitus, metabolic syndrome)
- BMI>30 kg/m2 or BMI<18.5 kg/m2
- Systematic autoimmune disorders
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Interventions
BIOLOGICALAutologous PRP intra ovarian infusion
Autologous PRP intra ovarian infusion
BIOLOGICALAutologous PFP intra ovarian infusion
Autologous PFP intra ovarian infusion
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03916978
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