Menopause Clinical Trials

76 recruiting

Menopause Trials at a Glance

95 actively recruiting trials for menopause are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 52 trials, with the heaviest enrollment activity in Minneapolis, São Paulo, and Boston. Lead sponsors running menopause studies include Mayo Clinic, University of Minnesota, and Brigham and Women's Hospital.

Browse menopause trials by phase

Treatments under study

About Menopause Clinical Trials

Looking for clinical trials for Menopause? There are currently 76 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Menopause trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Menopause clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 95 trials

Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting
Phase 4

Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women

EstrogenPremenopause
University of Delaware30 enrolled1 locationNCT06745466
Recruiting
Phase 1Phase 2

Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause

Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Not Applicable

Menopause Effects on Cortico-reticular Functioning

MenopauseHormone Replacement Therapy
University of Jyvaskyla20 enrolled1 locationNCT07500922
Recruiting
Phase 2Phase 3

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

MenopauseMenopause Related ConditionsCardiovascular+1 more
University of Colorado, Denver200 enrolled1 locationNCT06975111
Recruiting
Not Applicable

Exploration of the Effect of a Wheat Polar Lipid Complex on Vaginal Dryness in Healthy Postmenopausal Women

Vaginal DrynessMenopause Symptoms
Seppic110 enrolled1 locationNCT07386249
Recruiting
Not Applicable

Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause

Genitourinary Syndrome of Menopause
University of Nove de Julho60 enrolled1 locationNCT06873971
Recruiting

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

Body CompositionMenopauseCardiovascular (CV) Risk+2 more
University of California, San Francisco90 enrolled1 locationNCT07284082
Recruiting

An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies

Vasomotor Symptoms (VMS) Associated With Menopause
Bayer250 enrolled1 locationNCT06949553
Recruiting
Not Applicable

Exercise in Perimenopause to Improve Cognitive Health

Subjective Cognitive ComplaintsPerimenopause
University of British Columbia50 enrolled1 locationNCT07272174
Recruiting
Not Applicable

Smart Technology-Based Intervention and Monitoring of Physical and Mental Health in Early Postmenopausal Women

PostmenopausalMenopausePostmenopausal Disorder
YI-JU TSAI90 enrolled1 locationNCT07131215
Recruiting
Not Applicable

Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women

Post-menopauseGlucose Monitoring, ContinuousWhole Body Protein Metabolism+1 more
Nutrition 21, Inc.60 enrolled1 locationNCT07402382
Recruiting
Phase 4

Role of Menopause in Thermoregulation

MenopauseAging
Penn State University24 enrolled1 locationNCT06798571
Recruiting
Not Applicable

Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.

Sexual FunctionQuality of LifeGenitourinary Syndrome of Menopause+5 more
Mucosa Innovations, S.L.80 enrolled1 locationNCT06962345
Recruiting
Not Applicable

Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training

MenopauseHot FlashesBlood Pressure Regulation
Mayo Clinic30 enrolled1 locationNCT06743269
Recruiting
Not Applicable

The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.

MenopausePerimenopause
Leeds Beckett University72 enrolled1 locationNCT07135232
Recruiting
Phase 4

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445
Recruiting
Not Applicable

Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women

ObesityMenopauseOverweight+1 more
Chang Gung Memorial Hospital40 enrolled1 locationNCT07472881
Recruiting
Not Applicable

Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women

Mental HealthIntermittent FastingPerimenopause
American University of Beirut Medical Center140 enrolled1 locationNCT07481513
Recruiting
Not Applicable

Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Type 1 DiabetesPost-menopause
University of Alberta20 enrolled2 locationsNCT05188027