Menopause Clinical Trials

124 recruitingLast updated: July 17, 2026

There are 124 actively recruiting menopause clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, San Francisco, California, United States, Laguna Hills, California, United States. Updated daily from ClinicalTrials.gov.


Menopause Trials at a Glance

124 actively recruiting trials for menopause are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 69 trials, with the heaviest enrollment activity in Boston, San Francisco, and Laguna Hills. Lead sponsors running menopause studies include Mayo Clinic, Stratpharma AG, and University of Minnesota.

Browse menopause trials by phase

Treatments under study

About Menopause Clinical Trials

Looking for clinical trials for Menopause? There are currently 89 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Menopause trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Menopause clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 124 trials

Recruiting
Not Applicable

Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women

MenopauseHot FlashesBlood Pressure Regulation
Mayo Clinic30 enrolled1 locationNCT06743269
Recruiting

CARAMEL Observational Study

MenopauseCardiovascular (CV) RiskPerimenopause+3 more
Biogipuzkoa Health Research Institute3,000 enrolled6 locationsNCT07695376
Recruiting
Phase 2Phase 3

Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women

MenopauseInfertility, FemaleAmenorrhea+1 more
Genesis Athens Clinic100 enrolled1 locationNCT03916978
Recruiting
Phase 2Phase 3

Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients

Menopause Related ConditionsPremature Ovarian FailureMenopause, Premature+2 more
Genesis Athens Clinic100 enrolled1 locationNCT04031456
Recruiting
Phase 4

Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women

EstrogenPremenopause
University of Delaware30 enrolled1 locationNCT06745466
Recruiting
Not Applicable

Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause

PerimenopausePMDD
Texas Christian University20 enrolled1 locationNCT07688720
Recruiting

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

DysmenorrheaMenopauseEndometriosis+4 more
Samphire Group, Inc.50 enrolled1 locationNCT07679074
Recruiting
Not Applicable

Amygdala Insula Retraining in the Management of Perimenopause Symptoms

PerimenopauseMenopausal Complaints
Chronic Conditions Research Fund160 enrolled1 locationNCT07427459
Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting
Phase 4

Role of Menopause in Thermoregulation

MenopauseAging
Penn State University24 enrolled1 locationNCT06798571
Recruiting
Not Applicable

Hemodynamics After Resistance Training

Perimenopause
University of Michigan50 enrolled1 locationNCT07022340
Recruiting
Not Applicable

Hydration & Female Life Stages

DehydrationMenstruationHydration+3 more
PepsiCo Global R&D72 enrolled2 locationsNCT07653620
Recruiting
Not Applicable

Hot Flashes and Neurovascular Function in Women

MenopauseHot FlashesVasomotor System; Labile
Mayo Clinic120 enrolled1 locationNCT05193968
Recruiting
Not Applicable

Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy

Breast CancerPrehabilitationPostmenopause+1 more
Universidad de La Frontera68 enrolled2 locationsNCT06309290
Recruiting

Significance of Estrogen Status for Muscle Function, Physical Fitness, and Physiological Health Parameters - a Comparison of Age-matched Groups of Women Before and After Menopause.

MenopauseMuscle Mass and Strength
Mette Hansen30 enrolled1 locationNCT07649356
Recruiting
Not Applicable

Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Diabetes

MenopauseType 2 Diabetes
Lia Bally96 enrolled1 locationNCT06715514
Recruiting
Phase 4

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445
Recruiting
Not Applicable

Nitrate, Exercise and Vascular Function in Midlife Women

MenopauseHypertensionHealthy+1 more
University of Vienna54 enrolled1 locationNCT06527248
Recruiting
Not Applicable

12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07242430
Recruiting
Not Applicable

12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07235878