Menopause Clinical Trials

119 recruitingLast updated: June 17, 2026

There are 119 actively recruiting menopause clinical trials across 31 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, Madrid, Madrid, Spain, Aurora, Colorado, United States. Updated daily from ClinicalTrials.gov.


Menopause Trials at a Glance

119 actively recruiting trials for menopause are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 67 trials, with the heaviest enrollment activity in Boston, Madrid, and Aurora. Lead sponsors running menopause studies include Mayo Clinic, Stratpharma AG, and University of Minnesota.

Browse menopause trials by phase

Treatments under study

About Menopause Clinical Trials

Looking for clinical trials for Menopause? There are currently 86 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Menopause trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Menopause clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 119 trials

Recruiting
Not Applicable

Hot Flashes and Neurovascular Function in Women

MenopauseHot FlashesVasomotor System; Labile
Mayo Clinic120 enrolled1 locationNCT05193968
Recruiting
Not Applicable

Amygdala Insula Retraining in the Management of Perimenopause Symptoms

Perimenopause
Chronic Conditions Research Fund160 enrolled1 locationNCT07427459
Recruiting
Not Applicable

Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy

Breast CancerPrehabilitationPostmenopause+1 more
Universidad de La Frontera68 enrolled2 locationsNCT06309290
Recruiting
Not Applicable

Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Diabetes

MenopauseType 2 Diabetes
Lia Bally96 enrolled1 locationNCT06715514
Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting
Not Applicable

Nitrate, Exercise and Vascular Function in Midlife Women

MenopauseHypertensionHealthy+1 more
University of Vienna54 enrolled1 locationNCT06527248
Recruiting
Phase 4

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445
Recruiting
Not Applicable

12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07242430
Recruiting
Not Applicable

12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07235878
Recruiting
Phase 1

To Evaluate the Impact of Smoking on PK After Single-dose Oral Administration of GS1-144 Tablets .

Postmenopause
Changchun GeneScience Pharmaceutical Co., Ltd.24 enrolled1 locationNCT07534176
Recruiting
Not Applicable

Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women

Exercise TrainingMenopause Related Conditions
Mette Hansen30 enrolled1 locationNCT07617454
Recruiting
Not Applicable

MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal Osteoporosis

MenopauseOsteoporosis
Istituto Auxologico Italiano42 enrolled2 locationsNCT07616401
Recruiting

AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing

MenopauseGut MicrobiomeChronic Low-Grade Inflammation+2 more
Gulbenkian Institute for Molecular Medicine300 enrolled1 locationNCT07614542
Recruiting
Phase 4

Menopausal HT for Women Living With HIV (HoT)

MenopauseHIV Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections105 enrolled23 locationsNCT06856174
Recruiting

Brazilian Registry of Menopausal Health

Menopause
Science Valley Research Institute1,592 enrolled1 locationNCT07005648
Recruiting

Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function

Menopause
University of Minnesota100 enrolled1 locationNCT06490146
Recruiting
Phase 2

Finding Links Between Hot flASHes and CardioVascular Disease

Menopause-related Hot Flashes
Massachusetts General Hospital80 enrolled2 locationsNCT07077395
Recruiting
Not Applicable

Multimodal Program for Climacteric Women

climacteric syndromeMenopausePostmenopausal Symptoms+1 more
University of Valencia115 enrolled2 locationsNCT06419972
Recruiting

An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies

Vasomotor Symptoms (VMS) Associated With Menopause
Bayer250 enrolled1 locationNCT06949553
Recruiting
Not Applicable

Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being

Quality of LifeSleepGut Microbiota+3 more
King's College London20 enrolled1 locationNCT07599930