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RecruitingPhase 2Phase 3NCT03922542

Comparison of Standard vs. Accelerated Corneal Crosslinking

Randomized Comparison of Standard vs. Accelerated Corneal Crosslinking for Treatment of Progressive Keratoconus or Ectasia

Sponsor

Price Vision Group

Enrollment

510 participants

Start Date

Apr 16, 2019

Study Type

INTERVENTIONAL

Conditions

KeratoconusEctasia Corneal

Summary

The study objective is to compare accelerated and standard corneal crosslinking for treatment of progressive keratoconus or corneal ectasia.

Eligibility

Min Age: 10 Years

Inclusion Criteria1

  • Documented keratoconus or ectasia after refractive surgery

Exclusion Criteria6

  • Insufficient corneal thickness
  • Ocular condition that may predispose the eye to complications
  • History of chemical injury or delayed epithelial healing
  • Condition that would interfere with or prolong epithelial healing
  • Known sensitivity to treatment medications
  • Pregnancy
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Interventions

COMBINATION_PRODUCTriboflavin 0.1%

Use of riboflavin 0.1% eye drops and 9 mW/cm2 UVA light for 10 minutes

COMBINATION_PRODUCTRiboflavin 0.1%

Use of riboflavin 0.1% eye drops and 3 mW/cm2 UVA light for 30 minutes

Locations(1)

Price Vision Group

Indianapolis, Indiana, United States

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NCT03922542

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