RecruitingNot ApplicableNCT03941756

Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma

Prophylactic Lymphovenous Bypass Procedure Following Axillary Lymphadenectomy: A Prospective Observational Study


Sponsor

M.D. Anderson Cancer Center

Enrollment

252 participants

Start Date

Aug 14, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

This pilot trial studies whether a procedure called lymphovenous bypass would prevent lymphedema (arm swelling) in patients with inflammatory breast cancer or non-inflammatory breast cancer that has spread to nearby tissues or lymph nodes or melanoma. The lymphovenous bypass procedure creates a path for lymphatic fluid to flow away from the arms. It is usually done after a diagnosis of lymphedema. In this study, giving lymphovenous bypass before underarm lymph node surgery may help prevent lymphedema from forming.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a surgical procedure called lymphovenous bypass — done before underarm lymph node removal — can prevent lymphedema (painful arm swelling) in patients with breast cancer or melanoma who need lymph node surgery. Lymphedema is a common and often permanent side effect of removing lymph nodes under the arm. **You may be eligible if...** - You are at least 18 years old - You have inflammatory breast cancer or locally advanced non-inflammatory breast cancer requiring removal of underarm lymph nodes (axillary lymph node dissection) - OR you have melanoma of the arm or shoulder area requiring underarm lymph node removal - You are willing and able to participate **You may NOT be eligible if...** - You have already developed lymphedema - You have had prior surgery to the same underarm area - You have a condition that would make the bypass surgery unsafe - You are unwilling or unable to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGIndocyanine Green

Given IV

PROCEDURELymphangiography

Undergo lymphangiography

PROCEDURELymphovenous Bypass

Undergo LVB


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03941756


Related Trials