RecruitingNCT03949972

The FOrMe Registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry)


Sponsor

Prof. Dr. Paul Brinkkoetter

Enrollment

500 participants

Start Date

Apr 1, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

In a monocentric, later multicentric prospective approach the FOrMe registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry) aims to generate a longitudinal cohort of 150 pediatric cases of idiopathic nephrotic syndrome and 350 adult cases of biopsy-proven Minimal Change Disease (MCD) or Focal and Segmental Glomerular Sclerosis (FSGS) over 10 years. The registry will provide a repository for biomaterials such as blood samples, DNA, urine, feces, and tissue biopsies that will be accessible to collaborators to facilitate future research on pathogenesis, diagnostics, and treatment.


Eligibility

Inclusion Criteria6

  • written informed consent
  • or less years of age
  • idiopathic nephrotic syndrome
  • written informed consent
  • older or equal to 18 years of age
  • biopsy-proven primary or secondary FSGS or MCD or biopsy-proven recurrence of disease in kidney transplant.

Exclusion Criteria4

  • Prior kidney transplant without biopsy-proven recurrence
  • A clinical diagnosis of other glomerular disease resulting in secondary MCD or FSGS as judged by the treating physicians.
  • Refusal to provide written informed consent
  • (Anticipated) incompliance with visit schedule

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Interventions

OTHERBiosampling

Biosampling at initial visit and follow-up visits


Locations(12)

University Hospital of Cologne

Cologne, North Rhine-Westphalia, Germany

Uniklinik RWTH Aachen

Aachen, Germany

Charité University Hospital

Berlin, Germany

Kindernierenzentrum Bonn

Bonn, Germany

Kindernephrologie Dachau

Dachau, Germany

University Hospital Erlangen

Erlangen, Germany

University Hospital Essen

Essen, Germany

University Hospital Heidelberg

Heidelberg, Germany

Klinikum St. Georg

Leipzig, Germany

University Hospital Marburg

Marburg, Germany

University Hospital Münster

Münster, Germany

Klinikum Stuttgart

Stuttgart, Germany

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NCT03949972


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