RecruitingNot ApplicableNCT04571658

NEPTUNE Match Study

Implementing Precision Medicine for Glomerular Diseases in the Nephrotic Syndrome Study Network (NEPTUNE)


Sponsor

University of Michigan

Enrollment

375 participants

Start Date

May 2, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

NEPTUNE Match is an additional opportunity offered to NEPTUNE study participants to prospectively recruit and communicate patient-specific clinical trial matching with kidney patients and their physician investigators.


Eligibility

Min Age: 1 YearMax Age: 80 Years

Inclusion Criteria5

  • Consented and eligible participants in the biopsied or non-biopsied cohorts of the NEPTUNE observational study
  • Must be potentially eligible for the NEPTUNE Match partnering trials (e.g. if no trial is enrolling a participant under age 6, those under 6 are not eligible).
  • Note: NEPTUNE Match partnering trials and associated eligibility criteria are expected to be dynamic and change as trial protocols are developed, activated, and amended.
  • Regular nephrology healthcare provided at a NEPTUNE study site.
  • Willing and able to consent, and as appropriate assent, to participate in NEPTUNE Match

Exclusion Criteria2

  • Currently non-NEPTUNE observational study participants are not eligible to be matched to a clinical trial using these biomarker assessments.
  • \. Non-English or non-Spanish speaking

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Interventions

OTHERCommunication

The NEPTUNE Match study includes an interdisciplinary Communication Team that will translate findings from the Molecular Nephrology Board (MNB) to inform patients of the matching assessment with ongoing clinical trials. This team has considerable experience with conveying complex biomedical research information to patients and families and includes experts in precision nephrology, nephrology patient \[adult and pediatric\] communication, and health education.


Locations(16)

Emory University Hospital - Children's Hospital of Atlanta

Atlanta, Georgia, United States

John H. Stroger, Jr., Hospital of Cook County

Chicago, Illinois, United States

University of Kansas Medical Center

Kansas City, Kansas, United States

Johns Hopkins Medicine

Baltimore, Maryland, United States

University of Michigan

Ann Arbor, Michigan, United States

Children's Mercy Hospital

Kansas City, Missouri, United States

Northwell/Cohen's Children's Hospital

New Hyde Park, New York, United States

Columbia University Medical Center

New York, New York, United States

University of North Carolina Chapel Hill

Chapel Hill, North Carolina, United States

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Temple University

Philadelphia, Pennsylvania, United States

Medical University of South Carolina

Charlotte, South Carolina, United States

Seattle Children's Hospital

Seattle, Washington, United States

University of Washington Medical Center

Seattle, Washington, United States

Providence Sacred Heart Medical Center

Spokane, Washington, United States

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NCT04571658


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