RecruitingNCT03981575

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)


Sponsor

Virginia Commonwealth University

Enrollment

700 participants

Start Date

Jan 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

Building on previous work of the Myotonic Dystrophy Clinical Research Network (DMCRN), the present study seeks to overcome insufficient data on natural history; lack of reliable biomarkers; and incomplete characterization and limited biological understanding of the phenotypic heterogeneity of Myotonic Dystrophy 1 by examining strategies to improve the reliability by making further refinements in our sample collection and analysis procedures by developing strategies for managing patient heterogeneity going forward. Funding Source- FDA OOPD


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with dm1 and myotonic dystrophy 1. The study is currently recruiting participants at 17 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(17)

University of California, San Diego

La Jolla, California, United States

University of California, Los Angeles

Los Angeles, California, United States

University of Colorado - Denver

Denver, Colorado, United States

University of Florida

Gainesville, Florida, United States

University of Iowa

Iowa City, Iowa, United States

Kansas University Medical Center

Kansas City, Kansas, United States

University of Rochester

Rochester, New York, United States

Ohio State University

Columbus, Ohio, United States

Houston Methodist Neurological Institute

Houston, Texas, United States

Virginia Commonwealth University

Richmond, Virginia, United States

Université de Sherbrooke

Québec, Canada

Friedrich Baur Institute, Ludwig-Maximilians-Universität München

München, Germany

Centro Clinico NeMO

Milan, Italy

Radboud University Medical Center

Nijmegen, Netherlands

University of Auckland

Auckland, New Zealand

St. George's, University of London

London, United Kingdom

University College London

London, United Kingdom

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