RecruitingNCT03988764

Monogenic Diabetes Misdiagnosed as Type 1

Accurate Diagnosis of Diabetes for Appropriate Management

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Enrollment

5,000 participants

Start Date

Sep 24, 2019

Study Type

OBSERVATIONAL

Conditions

Diabetes Mellitus, Type 1 Monogenic Diabetes Neonatal Diabetes Maturity-onset Diabetes in the Young (MODY)Wolfram Syndrome Wolcott-Rallison Syndrome Mitochondrial Diabetes

Summary

The study has two aims: 1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection. 2. To discover novel genes whose mutations cause monogenic diabetes misdiagnosed as T1D.

Eligibility

Min Age: 1 DayMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This study identifies people who were diagnosed with type 1 diabetes before age 25 but may actually have monogenic diabetes — a rarer, inherited form of diabetes caused by a single gene mutation. Monogenic diabetes is often misdiagnosed as type 1 but can sometimes be managed with simpler treatments. **You may be eligible if...** - You were diagnosed with diabetes under the age of 25 - Your diabetes was diagnosed as type 1 or an undetermined type **You may NOT be eligible if...** - You have already had antibody testing that came back positive (confirming true type 1 diabetes) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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