RecruitingNCT03999138

MRI Assessment of Pulmonary Edema in Acute Heart Failure

Sponsor

University of Alberta

Enrollment

300 participants

Start Date

Jan 2, 2019

Study Type

OBSERVATIONAL

Conditions

Acute Heart Failure Pulmonary Edema With Heart Failure

Summary

Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or "increased lung water") in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using MRI scans to measure fluid buildup in the lungs (pulmonary edema) in people being treated for acute heart failure. The goal is to see if MRI can give doctors a better, more accurate picture of how well treatment is working compared to standard methods. **You may be eligible if...** - You are 18 or older - You are being treated in a hospital for acute heart failure with fluid in your lungs - You are receiving diuretics (water pills) to reduce fluid buildup - You were identified within 48 hours of starting treatment **You may NOT be eligible if...** - You have a contraindication to MRI (such as a pacemaker or certain metal implants) - You are too critically ill to be safely moved to the MRI scanner - You have moderate to severe dementia Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMRI

MRI studies (non-contrast) will consist of a free-breathing localizer (\~10 seconds) followed by a free-breathing yarnball water density scan, for a total MRI time of \< 3 minutes.

Locations(2)

University of Alberta

Edmonton, Alberta, Canada

University of Ottawa Heart Institute

Ottawa, Ontario, Canada

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NCT03999138

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