Lidocaine Infusion in Pancreatic Cancer

This trial tests whether giving intravenous lidocaine (a local anesthetic commonly used in numbing injections) during surgery for pancreatic cancer affects how well patients do afterward — including pain control, recovery time, and possibly even cancer outcomes. Lidocaine has anti-inflammatory properties that may do more than just numb pain. **You may be eligible if...** - You have been diagnosed with pancreatic cancer that is being surgically treated - You are scheduled for surgery at a participating center - You have had prior systemic treatments for metastatic disease (these are permitted) **You may NOT be eligible if...** - You have a severe allergy to local anesthetics (amide-linked type) - You have certain heart rhythm problems (such as second or third degree heart block) - You are taking class I antiarrhythmic drugs (such as quinidine or flecainide) - You have taken amiodarone (a heart drug) in the past - You are in very poor overall health (ASA physical status greater than 3) Talk to your doctor to see if this trial is right for you.