RecruitingNCT04058782

Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction


Sponsor

University Hospital, Lille

Enrollment

2,000 participants

Start Date

Feb 17, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

Risk assessment after myocardial infarction is critical in daily practice and evolution toward heart failure especially diastolic heart failure remains a key issue. All consecutive patients with myocardial infarction (either STEMI or NSTEMI but excluding type 2 MI) presenting at university hospital of Lille within 48 hours after symptom onset will be recruited in the RIGID-MI registry. The RIGID-MI study proposes to deeply evaluate at 1 month after MI: peripheral vascular disease, vascular stiffness, ventriculo-arterial coupling and other usual risk factors. The main objective is to identify clinical, biological and imaging parameters associated with poor prognosis, especially evolution toward diastolic heart failure, recurrence of MI, and bleeding.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether measuring artery stiffness in patients who have recently had a heart attack (myocardial infarction) can help predict future health risks more accurately. Researchers will assess blood vessel stiffness and track patient outcomes over time. **You may be eligible if...** - You have had a heart attack (myocardial infarction) within the last 48 hours - You are enrolled in French national health insurance - You are willing to participate and sign consent **You may NOT be eligible if...** - Your heart attack occurred more than 48 hours ago - You have a Type 2 myocardial infarction (caused by something other than a blocked artery, such as a blood supply imbalance) - You are pregnant or breastfeeding - You do not have French national health insurance - You are under legal guardianship Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERImaging evaluation for vascular assessment

At 1month after MI, Blood sample for total blood, plasma and PBMC collection, ECG, 3D-trans thoracic echocardiography for ventriculo-arterial coupling assessment, Vascular doppler for peripheral artery disease assessment, Arterial stiffness evaluation, Bilateral transcranial doppler for HITS evaluation


Locations(1)

Institut Coeur-Poumon, CHU

Lille, France

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NCT04058782


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