Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction
University Hospital, Lille
2,000 participants
Feb 17, 2020
OBSERVATIONAL
Conditions
Summary
Risk assessment after myocardial infarction is critical in daily practice and evolution toward heart failure especially diastolic heart failure remains a key issue. All consecutive patients with myocardial infarction (either STEMI or NSTEMI but excluding type 2 MI) presenting at university hospital of Lille within 48 hours after symptom onset will be recruited in the RIGID-MI registry. The RIGID-MI study proposes to deeply evaluate at 1 month after MI: peripheral vascular disease, vascular stiffness, ventriculo-arterial coupling and other usual risk factors. The main objective is to identify clinical, biological and imaging parameters associated with poor prognosis, especially evolution toward diastolic heart failure, recurrence of MI, and bleeding.
Eligibility
Inclusion Criteria3
- Signed informed consent
- Affiliated to national health insurance (French social security number)
- Presenting with MI within 48 hours of symptom onset
Exclusion Criteria6
- Patient under curatorship
- Type 2 MI
- Presenting with MI after 48 hours of symptom onset
- Pregnancy or lactating
- Refuse to participate
- No national health insurance (No French social security number)
Interventions
At 1month after MI, Blood sample for total blood, plasma and PBMC collection, ECG, 3D-trans thoracic echocardiography for ventriculo-arterial coupling assessment, Vascular doppler for peripheral artery disease assessment, Arterial stiffness evaluation, Bilateral transcranial doppler for HITS evaluation
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04058782