Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH)

This study is testing the feasibility of new clinical trial methods and technology for studying pulmonary hypertension (PH) — a condition where blood pressure in the arteries of the lungs is abnormally high. The study is not testing a specific drug but is testing whether new trial designs and digital tools can work effectively in this patient population. **You may be eligible if...** - You have been diagnosed with pulmonary hypertension (Groups I, II, III, or IV) - You are at least 18 years old - Your kidney function (eGFR) is above 25 - Your BMI is below 35 - You have adequate pulmonary artery size (branch at least 7mm) - You have a negative pregnancy test if you are of childbearing age - You are willing to comply with study requirements **You may NOT be eligible if...** - You have Group IV pulmonary hypertension (chronic thromboembolic pulmonary hypertension) - You have an active infection, blood clot (pulmonary embolism or DVT), or a major cardiovascular event within the past 2 months - You have a known clotting disorder or allergy to aspirin or clopidogrel - You have a mechanical heart valve or recently placed cardiac device Talk to your doctor to see if this trial is right for you.